Prostaglandin Receptor Modulators

Cat.No. Product Name Information Product Use Citations Product Validations
S3346 1-Methylnicotinamide chloride

1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride is an active endogenous metabolite of nicotinamide that exhibits anti-inflammatory and anti-thrombotic activities. 1-Methylnicotinamide enhances tumour vasculature formation and markedly increases prostacyclin (PGI2) generation.

Oncol Rep, 2021, 45(6)110
S0541 Dazoxiben hydrochloride Dazoxiben hydrochloride (HCl) is a potent, selective and orally active inhibitor of thromboxane (TX) synthase. Dazoxiben inhibits TXB2 production in clotting human whole blood with IC50 of 0.3 μM and causes parallel enhancement of PGE2 production.