Home GPCR & G Protein Prostaglandin Receptor

Prostaglandin Receptor Inhibitors

Cat.No. Product Name Information Product Use Citations Product Validations
S6649 E7046 (ER-886406) E7046 (ER-886406, Palupiprant, AN0025) is a selective inhibitor of the prostaglandin E2 (PGE2) receptor EP4 with IC50 of 13.5 nM and Ki of 23.14 nM.
Cell Mol Life Sci, 2022, 79(6):303
S2496 Ozagrel Ozagrel (OKY-046) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with an IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.
S6496 Genz-123346 free base Genz-123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1, the first step in the biosynthesis of gangliosides and other glycosphingolipids.
E1477 EP4-IN-1 EP4-IN-1 is a potent prostanoid EP4 receptor inhibitor. It exhibits prospects in tumour immunity and anti-inflammatory analgesia research.
S5594 (-)-(S)-α-terpineol (-)-(S)-α-terpineol, a natural monoterpene, is the major component of essential oils of several species of aromatic plants such as Origanium vulgare L. and Ocimum canum Sims which are widely used for medicinal purposes. It is widely used in the manufacturing of cosmetics, soaps, perfumes, antiseptic agents and is considered one of the most frequently used fragrance compounds. α-TPN has anticholinergic action and can block the interaction between PGE2 and GM1 receptors and cholera toxin.
S0141 NQ301 NQ301 (Compound 211), an antiplatelet and antithrombotic agent, is a selective CD45 inhibitor with IC50 of 200 nM. This compound inhibits thromboxane A2 receptor (TXA2) and synthase activity in rabbit platelets.
J Extracell Vesicles, 2021, 10(5):e12078
S2067 Ozagrel HCl Ozagrel HCl (OKY-046) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with an IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.
S5252 Ozagrel sodium Ozagrel sodium (KCT-0809, Cataclot, Xanbo) is a thromboxane A2 synthase (CYP5) inhibitor with neuroprotective properties.