Sigma Receptor Activators

Cat.No. Product Name Information Product Use Citations Product Validations
E7418 Noscapine Noscapine ((S,R)-Noscapine) is an alkaloid derived from the opium poppy (Papaver somniferum) and is a centrally acting antitussive opiate derivative. It is a non-competitive antagonist of the bradykinin B2 receptor. This compound also exhibits neuroprotection by activating sigma-1 opioid receptors, which help suppress intracellular NO levels and calcium, thereby providing protection against ischaemic injury.