Parasite Inhibitors
| Cat.No. | Product Name | Information | Product Use Citations | Product Validations |
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| S5816 | Pyrvinium pamoate | Pyrvinium pamoate (Pyrvinium embonate) is an anthelmintic effective for pinworms. |
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| S4610 | Mebendazole | Mebendazole is a synthetic benzimidazole derivate and anthelmintic agent. This compound interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake. |
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| S4104 | Diminazene Aceturate | Diminazene (Diminazene diaceturate) is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties. |
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| S5948 | Amodiaquine | Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or Parasite DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria. |
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| S4068 | Tinidazole | Tinidazole (CP12574) is an anti-Parasite drug. |
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| S1851 | Oxibendazole | Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets. |
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| S1691 | Praziquantel | Praziquantel is an anthelmintic effective against flatworms. |
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| S3741 | Benznidazole | Benznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with Parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis. |
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| S4999 | Avermectin B1 | Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. |
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| S2028 | Diclazuril | Diclazuril (R-64433) is an anti-coccidial drug. |
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| S1830 | Oxfendazole | Oxfendazole (RS-8858, Fenbendazole sulfoxide) is a broad spectrum benzimidazole anthelmintic. |
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| S5345 | (+/-)-nerolidol | (+/-)-nerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-Microbiology, anti-biofilm, anti-Parasite, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumour, anti-nociceptive and anti-inflammatory properties. |
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| S3713 | Moxidectin | Moxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari. |
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| S5055 | Milbemycin Oxime | Milbemycin Oxime is a broad spectrum anti-Parasite drug that is active against worms (anthelmintic) and mites (miticide). |
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| S3889 | Arteether | Arteether is a well-known antimalarial drug which acts by producing free radicals within the malarial Parasite. |
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| S3591 | Eprinomectin | Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity. |
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| S5094 | Maduramycin Ammonium | Maduramicin, which could be isolated from the actinomycete Actinomadura rubra, is an antiprotozoal agent used in veterinary medicine to prevent coccidiosis. |
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| S0467 | Emodepside | Emodepside (QHT06, BAY 44-4400, PF 1022-221), a semisynthetic derivative of PF1022A, is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. This compound activates Ca-dependent SLO-1-like K channels. |
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| S5247 | Selamectin | Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate Parasite through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas. |
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| S2468 | Fenbendazole | Fenbendazole (Fenbendazol, Phenbendasol) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal Parasite with an IC50 of about 0.01 μg/mL. | ||
| S2501 | Pyrantel Pamoate | Pyrantel Pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections. | ||
| S4141 | Dinitolmide | Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug. | ||
| S4044 | Toltrazuril | Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites. | ||
| S4094 | Tetramisole HCl | Tetramisole (R-829, (")-Tetramisole hydrochloride) is a mixture of dextro- and levo isomers used as an anthelmintic. | ||
| S3999 | α-santonin | α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent. | ||
| S4866 | Nicarbazin | Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-Parasite drug. | ||
| E3182 | Carica Papaya Fruit Extract | Carica Papaya Fruit Extract is extracted from the fruit of Carica Papaya, which has proven antihelminthic and anti-amoebic activities. | ||
| S4876 | Robenidine Hydrochloride | Robenidine Hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) is an anticoccidial agent mainly for poultry. | ||
| E3101 | Toosendan Fructus Extract | Toosendan Fructus Extract is extracted from Fructus Meliae Toosendan, which has potent anticoccidial effects and also acts as an alternative anticoccidial agent for avian coccidiosis control. | ||
| S4145 | Decoquinate | Decoquinate is a coccidiostat. | ||
| S4599 | Benzyl benzoate | Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite Sarcoptes scabiei. | ||
| S0081 | DDD107498 | DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. This compound exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium Parasite. | ||
| S4167 | Cyromazine | Cyromazine (Cyromazin, CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. | ||
| S5722 | Oxantel Pamoate | Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting. | ||
| S4898 | Sulfalozine sodium | Sulfalozine sodium (Sulfaclozine sodium, Sulfachlopryrazine sodium) is an antiprotozoal useful in coccidiosis research. | ||
| S4882 | Resorantel | Resorantel is a safe, hydroxybenzanilide cestocide highly effective against Moniezia and Thysaniezia spp. and moderately effective against Paramphistomum spp. | ||
| S5017 | Oxyclozanide | Oxyclozanide (Oxiclozanidum, Zanil, Oxyclozanid, Zanilox) is a salicylanilide anthelmintic and mitochondrial uncoupling anthelmintic drug approved for veterinary use. | ||
| E7715 | Ivermectin B1a | Ivermectin B1a is a potent broad-spectrum antiparasitic agent, widely used to treat nematode and arthropod infections in humans and animals. It contributes to the overall effectiveness of commercial ivermectin in treating diseases like onchocerciasis, lymphatic filariasis, and various intestinal worm infections. | ||
| E7970 | Pyronaridine | Pyronaridine is a lipophilic Mannich base with potent antimalarial and potential antiviral activities. It inhibits haemozoin formation in Plasmodium by binding haematin, leading to Parasite death. This compound is also active against P. falciparum and has shown efficacy against Echinococcus granulosus infections. | ||
| S3707 | Ethopabate | Ethopabate (ETP, Ethyl pabate) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens. | ||
| S5031 | Sulfaquinoxaline sodium | Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na) is the sodium salt of sulfaquinoxaline, which is often used as a drug to prevent coccidiosis in poultry, swine, and sheep by inhibiting the synthesis of nucleic acids and proteins in microorganisms. | ||
| S5093 | Rafoxanide | Rafoxanide (Disalan, Ranide, Flukanide, Bovanide) is a salicylanilide used as an anthelmintic, being effective treatment for the control of fluke infections in animals. | ||
| S5092 | Febantel | Febantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) is a prodrug that is metabolised to fenbendazole and oxfendazole, which are undoubtedly the active parasiticides. | ||
| S5557 | Aklomide | Aklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry. | ||
| S4443 | Piperazine adipate | Piperazine adipate is a broad spectrum anthelmintic agent that inhibits malate oxidation in Ascaridia galli and Heterakis gallinae. | ||
| S4564 | Diethylcarbamazine citrate | Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several Parasite and does not contain any toxic metallic elements. | ||
| S1265 | SQ109 | SQ109 is a potent inhibitor of the trypomastigote form of the Parasite, with IC50 for LLC-MK2 culture-derived trypomastigotes of 50±8 nM, targets MmpL3 (mycobacterial membrane protein large 3) in Mycobacterium tuberculosis. | ||
| S7379 | E-64 | E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. This compound induces oxidative stress and apoptosis in Filarial Parasite. |
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| S3079 | Atovaquone | Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia. |
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| S1837 | Flubendazole | Flubendazole (Flumoxanal, NSC 313680) is an Autophagy inducer by targeting Atg4B, used to treat internal Parasite and worm infection. |
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| E3814 | Phyllanthus Urinaria Extract | Phyllanthus Urinaria Extract is extracted from Phyllanthus urinaria (L.), which is used to treat jaundice, diabetes, malaria, and liver diseases. |
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| S4422 | Nitenpyram | Nitenpyram(Bestguard,Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat Parasite of livestock and pets. |
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| E3040 | Stemonae Extract | Stemonae Extract is extracted from Radix Stemonae, has been widely used as an oral anti-tussive agent in traditional Chinese medicine (TCM) for thousands of years with pharmacological effects as anti-tussive, anti-tuberculous, anti-Bacterial, anti-Fungal and anti-helminthic. | ||
| E3085 | Dichroae Radix Extract | Dichroae Radix Extract is drawed from Dichroae radix, exhibits good clinical efficacy in treatments as an antimalarial, expectorant or antifebrile agent in Chinese medicine, and it also has an anticoccidial effect in chickens infected by coccidiosis when used alone or as the main herb to formulate a complex. | ||
| E3111 | Tribulus Terrestris Extract | Tribulus Terrestris Extract is extracted from Tribulus Terrestris, which has anti-inflammatory, analgesic, antispasmodic, anticancer, antibacterial, anthelmintic, larvicidal, and anticariogenic activities. | ||
| E3145 | Kochiae Fructus Extract | Kochiae Fructus Extract is obtained from dried fruit of Kochia scoparia (L.) Schrad., broom cypress fruit), has attracted considerable attention for its pharmacological activities, including antiinflammation, antidiabetics, insecticide, antianaphylaxis, antipruritic and anti-rheumatoid arthritis. | ||
| E3165 | Rabdosiae Rubescentis Herba Extract | Rabdosiae Rubescentis Herba Extract is drawed from the dried aerial part of genus Rabdosia rubescens (Hemsl.) Hara of the Lamiaceae family, which possesses several biological activities, such as anti-Bacterial, anti-Parasite, anti-inflammation, and anticancer. | ||
| S4389 | Bephenium Hydroxynaphthoate | Bephenium (NSC 759245) is an activator of B-type Acetylcholine receptor (AChR). Bephenium selectively activates the Hco-L-AChR1 subtype made of Hco-UNC-29.1, Hco-UNC-38, Hco-UNC-63, Hco-ACR-8 subunits. Bephenium Hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis. |
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