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GluR Inhibitors

Cat.No. Product Name Information Product Use Citations Product Validations
S4716 Evans Blue Evans Blue (Direct Blue 53, C.I.23860) is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist.
Cell Commun Signal, 2025, 23(1):420
Int J Nanomedicine, 2024, 19:6677-6692
J Biol Chem, 2022, 298(12):102699
S6906 Capric acid Capric acid (DA, Decanoic acid, Decylic acid), a component of medium-chain triclycerides occurring naturally in coconut oil and palm kernel oil, contributes to seizure control through direct AMPA receptor inhibition. This compound is also a modulating ligand for PPARs. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.
Pharmaceuticals (Basel), 2023, 16(5)692
S2860 IEM 1754 2HBr IEM 1754 2HBr is a selective AMPA/kainate receptor blocker for GluR1 and GluR3 with an IC50 of 6 μM.
E4619 Basimglurant Basimglurant (RG7090, CTEP Derivative) is a potent and selective negative allosteric modulator of mGlu5, with a Kd of 1.1 nM. It inhibits the function of mGluR5, thereby regulating glutamatergic neurotransmission.