Casein Kinase Activators

Cat.No. Product Name Information Product Use Citations Product Validations
E6444New SSTC3 SSTC3 is a potent activator of casein kinase 1α (CK1α) with a Kd of 32 nM that inhibits WNT signalling with an EC50 of 30 nM. It attenuates CRC cell growth through CK1α-dependent WNT pathway inhibition, offering an improved therapeutic index for targeting WNT-driven tumours.
S3143 Pyruvic acid

Pyruvic acid (Acetylformic acid) is an important organic chemical intermediate that plays a role in cardiomyocyte pathophysiology and therapy. This compound markedly increases the level of lactate dehydrogenase (LDH) and creatine kinase (CK) and reduces the level of Ca2+Mg2+-ATPase and Na+K+-ATPase.