Home MAPK -Protein Tyrosine Kinase MEK MEK5-Selective Inhibitors

MEK5-Selective Inhibitors

  • MEK1
  • MEK1/2
  • MEK2
  • MEK5
Cat.No. Product Name Information Selective / Pan IC50 / Ki
S1531 BIX 02189 BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2. Selective MEK5, IC50: 1.5 nM
S1530 BIX 02188 BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2. Selective MEK5, IC50: 4.3 nM