Fragment Library

Cat.No.L1600

A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).

Customise Your Library:

Specific Compounds
Quantities
96 or 384 well Plate Map
Dry/solid or DMSO solution

Cited by 3 Publications

Fragment Library Contents

Description & Advantages

• A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD)

• FBDD has emerged as an alternative approach for high-throughput screening (HTS) in discovering drug

• These fragments with low molecular weight are extremely suitable for screening clinical candidates with good drug-like properties,and more and more compounds discovered by FBDD are entering the clinic

• FBDD can save research cost and make it easier to screen high-performance drugs

	Range	Average
MolWeight	92 to 291	164.8
LogP	<3.8	1.5
Num_H_Acceptors	0 to 6	2.4
Num_H_Donors	0 to 3	1
Num_RotatableBonds	0 to 8	1.5
PSA	0 to 99	8

Product Details

Formulation	1015 compounds pre-dissolved in 10mM DMSO
Container	96 Deep Well Plate Sealed With Aluminium Foil
Stability	12 months	-20°C	in DMSO
Stability	24 months	-80°C	in DMSO
Shipping	Blue ice or dry ice

Case Studies using Selleck Compound Libraries

Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF

Nature.2019;574(7777):268-272
Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF

Nat Commun. 2019 16;10(1):2197
Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF

Cell Res. 2019;29(9):739-753
Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF

Mov Disord. 2019;34(3):323-334
Application of Epigenetics Compound Library in acute lymphoblastic leukaemia (This article was published in Blood (IF

Blood. 2019 17;134(16):1323-1336
Application of Inhibitor Library in tumour immunology (This article was published in Cancer Immunol Res (IF

Cancer Immunol Res.2017;5(9):790-803