For research use only. Not for use in humans.

Telisotuzumab (Anti-HGFR / c-Met)

Cat.No.A2467 Purity:99%

Telisotuzumab (Anti-HGFR / c-Met) is a monoclonal antibody that targets c-Met. MW: 145.64 KD.

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Quality Control

Batch: A246701 Purity: 99% Protein concentration: 14.76mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Specificity

Name	Citation	c-Met	Others
Foretinib	94	++++	KDR,Tie-2,VEGFR3/FLT4
PHA-665752	96	++	RON,Flk1
SU11274	67	+
SGX-523	136	+++
BMS-777607	63	+++	Axl,RON,Tyro3
Tivantinib	49	+
JNJ-38877605	54	+++
PF-04217903	22	++
MGCD-265 analog	12	++++	RON,VEGFR2,VEGFR1
BMS-754807	54	++	Insulin Receptor,IGF-1R,TrkB
BMS-794833	2	+++	VEGFR2
AMG-208	0	++
MK-2461	4	++++	c-Met (Y1235D),c-Met (Y1230C),c-Met (N1100)
Golvatinib (E7050)	8	+	VEGFR2
AMG-458	0	++++
Tepotinib	23	+++
NVP-BVU972	1	+
Savolitinib (AZD6094)	19	++	p-Met
S49076	1	++++	Mer,Axl,FGFR3
Merestinib (LY2801653)	11	+++
AMG 337	2	++++
NPS-1034	3	+	Axl

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Telisotuzumab (Anti-HGFR / c-Met) is a monoclonal antibody that targets c-Met. MW: 145.64 KD.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Molecular Weight	145.64 kDa
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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