Otilimab (Anti-CSF2 / GM-CSF)
Synonyms: GSK 3196165; MOR103
Otilimab (GSK 3196165) is a humanised monoclonal antibody targeting GM-CSF (granulocyte-macrophage colony-stimulating factor). Otilimab neutralises the biological function of GM-CSF by blocking the interaction of GM-CSF with its cell surface receptor. MW: 145.5 KD.
Quality Control
Mechanism of Action
| Description |
Otilimab (GSK 3196165) is a humanised monoclonal antibody targeting GM-CSF (granulocyte-macrophage colony-stimulating factor). Otilimab neutralises the biological function of GM-CSF by blocking the interaction of GM-CSF with its cell surface receptor. MW: 145.5 KD.
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Product Details
| CAS No. | 1638332-55-4 |
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| Molecular Weight | 145.5 kDa |
| Isotype | Human IgG1 |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage | Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
Comparison of Clones for
*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)
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