For research use only. Not for use in humans.

Emapalumab (anti-IFNγ)

Synonyms: Gamifant Cat.No.A2041 Purity:99%

Emapalumab (anti-IFNγ), a monoclonal antibody directed against IFNγ, is the first global approval for the treatment of paediatric and adult patients with primary haemophagocytic lymphohistiocytosis (HLH) with refractory.

3 Citations

17 Nobel Prize winners
have used Selleck products

Shimon Sakaguchi

Nature Communications 2025;16, Article number:1325

David Baker

Dev Cell 2023;58(20):2163-2180.e9.

Michael Houghton

Cell Chem Biol 2020;27(7):780-792.e5

David Julius

Cell 2017;185-198.e16

Charles M. Rice

Cell 2018;172(3):423-438.e25

Quality Control

Batch: Purity: 99% Protein concentration: 9.24mg/ml Endotoxin Level: ＜1EU/mg

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Emapalumab (anti-IFNγ), a monoclonal antibody directed against IFNγ, is the first global approval for the treatment of paediatric and adult patients with primary haemophagocytic lymphohistiocytosis (HLH) with refractory.
References	[1] https://pubmed.ncbi.nlm.nih.gov/31537529/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1709815-23-5
Molecular Weight	135 KD
Isotype	Human IgG1
Application	Emapalumab (anti-IFNγ)
Sterility	0.2 μM filtered
Formulation	PBS Buffer, PH 7.4
Storage	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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