For research use only. Not for use in humans.

Domagrozumab (Anti-GDF8 / Myostatin)

Synonyms: PF-06252616 Cat.No.A2826 Purity:99%

Domagrozumab (Anti-GDF8 / Myostatin) is an anti-myostatin humanized monoclonal antibody with a KD value of 2.6 pM for human myostatin. Domagrozumab has the potential to be used in research of duchenne muscular dystrophy (DMD). MW : 143.96 KD.

Quality Control

Batch: A282601 Purity: 99% Protein concentration: 8.86mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Mechanism of Action

Description	Domagrozumab (Anti-GDF8 / Myostatin) is an anti-myostatin humanized monoclonal antibody with a KD value of 2.6 pM for human myostatin. Domagrozumab has the potential to be used in research of duchenne muscular dystrophy (DMD). MW : 143.96 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/29121992/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1629605-31-7
Molecular Weight	143.96
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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