For research use only. Not for use in humans.

Anti-TGFb1 (NIS793)

Synonyms: NIS793 Cat.No.A3071 Purity:99%

Anti-TGFb1 (NIS793) is a monoclonal antibody targeting TGF-β. It can be used in metastatic melanoma and non-small cell-lung cancer. MW :143.78 KD

Quality Control

Batch: A307101 Purity: 99% Protein concentration: 5.403mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Specificity

Name	Citation	ALK1	ALK2	ALK3	ALK4	TGFβRI/ALK5	ALK6	TGFβRII	TGF-β	Smad3	Others
SB431542	799					+
LDN-193189	262	++++	++++	+++			+++
Galunisertib (LY2157299)	192					++
LY2109761	137					++		+
SB-525334	116					+++
SB505124	37				+	++
GW788388	25					+++
LY364947	49					++		+			RIPK2,CK1δ,MLK-7K
RepSox (E-616452)	82					++++
LDN-193189 Dihydrochloride	103	++++	++++	+++			+++
K02288	24	++++	++++	++			+++
LDN-214117	4		++
SD-208	21					++
Vactosertib (TEW-7197)	28				+++	+++
ML347	5	++	++
LDN-212854	7	++++	++++	+	+	+
DMH1	61		+
Alantolactone	3									✔	STAT3
SIS3 Hydrochloride	85									✔
Hesperetin	4								✔		Histamine receptor

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Anti-TGFb1 (NIS793) is a monoclonal antibody targeting TGF-β. It can be used in metastatic melanoma and non-small cell-lung cancer. MW :143.78 KD
References	[1] https://pubmed.ncbi.nlm.nih.gov/35353346/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Isotype	Human IgG1
Source	CHO
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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