Home Metabolism Carbonic Anhydrase Carbonic Anhydrase I-Selectief Inhibitors

Carbonic Anhydrase I-Selectief Inhibitors

  • Carbonic Anhydrase I
  • Carbonic Anhydrase II
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase IX
  • Carbonic Anhydrase XII
Cat.nr. Productnaam Informatie Selectief / Pan IC50 / Ki
S2603 Tioxolone Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM. Selective CAI, Ki: 91 nM
S4039 Methazolamide Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. Pan hCAI, Ki: 50 nM
S2866 U-104 U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II. Pan CAI, Ki: 5.08 μM
S1375 Dorzolamide HCl Dorzolamide HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent. Pan Carbonic anhydrase I, Ki: 6000 nM